The systematic review summarizes the clinical characteristics of 158 pediatric patients stratified by both the presence of symptoms (asymptomatic versus symptomatic) and by age groups (greater and less than 10 years). No deaths were reported and most of the cases recovered.
However, males are more likely to have an asymptomatic infection, and abnormal laboratory results have identified symptomatic pediatric COVID-19 better than asymptomatic one. 7 September 2020. BMJ.
Covid-19: UK studies find gastrointestinal symptoms are common in children
Gastrointestinal symptoms are common in children infected with SARS-CoV-2 and could trigger tests for the virus, the researchers say.Published in August 2020, but on cases through April 30. A systematic review and meta-analysis of children with Coronavirus Disease 2019 (COVID-19)
Pediatric patients with COVID-19 may experience milder disease with atypical clinical manifestations and rarely lymphopenia. The high incidence of critical illness and vomiting need attention in children under 1 year of age. 48 studies totaling 5,829 pediatric patients were included. July 15, 2020. Pediatrics.
COVID-19 Disease Severity Risk Factors for Pediatric Patients in Italy
ISS study on Covid in Italian children: pediatric cases represent 1.8% of the total, the median age is 11 years, 13.3% of cases were hospitalized, pre-existing diseases double the risk of greater severity of the disease.
- The photograph of pediatric cases in Italy was taken in the study published in the journal Pediatrics by the Istituto Superiore di Sanità, with the participation of the Ministry of Health and the Bambino Gesù Hospital in Rome.
- The data suggest that pediatric cases of COVID-19 are less severe than other age groups, however age ≤ 1 year and the presence of pre-existing pathological conditions represent risk factors for disease severity, therefore control measures should be maintained and eventually implemented to protect the most vulnerable children. 25 June 2020.
The Lancet Child & Adolescent Health. COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study This study is the first multinational and multicenter study in children with COVID-19 and provides a detailed overview of SARS-CoV-2 infection in children in Europe during the initial peak of the pandemic, which was facilitated by the collaboration of 82 centers. in 25 European countries.
The study has several key findings
First, the data show that COVID-19 is generally a mild disease in children, including infants. Second, the study found that a substantial percentage (8%) of children develop severe illness, requiring intensive care support and prolonged ventilation.
Several predisposing factors have been identified for requiring intensive care support. Third, the study confirms that fatal outcome is rare in children. There has been considerable variability in drug use between antivirals and immunomodulators, reflecting current uncertainties regarding specific treatment options.